Uzaki-chan is a fairly standard romcom with a simple basis of a loner getting harassed by his overly energetic underclassman who wants to hang out. This kind of story has been done many times before and will be done many more times, so why should you watch this one? It's pretty fun.
It's very easy to dislike this anime, maybe you're just not a fan of silly romcom anime, maybe you feel infuriated because Uzaki's breasts are large, maybe you think she's annoying as hell. If you do think things along these lines, I wouldn't recommend bothering,
Uzaki isn't an incredible anime, it's just pretty alright. The jokes are pretty funny, although a handful of them are somewhat ecchi, the characters work, although they may not be the most unique or interesting, the show looks and sounds pretty good, although it may not be too memorable. The show isn't the kind of thing you should sit down to expecting some amazing tear-jerking romance anime with funny moments, it is a show where the comedy aspect overpowers the romance aspect, which is mainly present as a nice, sweet aftertaste to the silly jokes. The silly jokes themselves could be very hit or miss, it depends, do you actually like romcom humor? The jokes mainly consist of Uzaki and Sakurai being pushed into uncomfortable and embarrassing situations by either the fault of one of them or the various supporting characters who exist only to put them in these situations, the latter probably being the best in terms of comedy.
A lot of people seem to have a problem with the show due to Uzaki's annoying attitude and how she pushes Sakurai to do things with her when he would rather be left alone, having actually watched the show, I feel like I can safely say that he doesn't really mind all that much, being bugged to do things with Uzaki, he finds her as annoying as many of the viewers do, but if he really, truly, wanted to be left alone, he could pretty easily make her go away. It is shown in the anime that he actually does enjoy her company, but maybe you, the viewer, do not, and if that is the case, I would suggest just not watching the show. Ultimately, Uzaki and Sakurai care a lot about each other and worry about each other, I would say that there is an actual amount of development between their relationship as well.
In terms of what I like about the anime, there's quite a bit that makes it feel worthwhile to me. The jokes are pretty funny, the chemistry between Uzaki and Sakurai, while it may seem to be very little at first, is at least decent. There are a few emotional moments that, while not incredible, were at least a little bit touching to me. The animation is fairly good, the soundtrack is okay, the opening song is nice. There's not much outstanding to say about this anime, though I do definitely appreciate that it takes place in college and work settings instead of the much overdone high school and middle school settings, definitely makes the atmosphere a lot more comfortable and relatable to me.
Uzaki-chan wa Asobitai! is a fairly fun anime, and if you just want to have a laugh at funny embarrassing romcom shenanigans, give it a try! I definitely enjoyed it, and will be watching season 2 as well.

~~Uzaki-chan's design actually is pretty good, it's okay to say you just don't like tits and short hair, nobody will judge you.~~
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